Jul 29, - Mary-Louise Parker. Mary-Louise Parker, (born August 2, , Fort Jackson, South Carolina, U.S.), American actress of stage, screen, and television who was noted for bringing integrity and depth to her performances. Parker grew up in South Carolina and studied acting at the North Carolina School of the Arts. Mary-Louise Parker Biography. Mary-Louise Parker is an American Emmy and Tony Award-winning actress known for her role on the Showtime television show Weeds.